International Journal on Science and Technology

E-ISSN: 2229-7677     Impact Factor: 9.88

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 16 Issue 2 April-June 2025 Submit your research before last 3 days of June to publish your research paper in the issue of April-June.

Formulation & Evalution of Anti Fungal gel using Datura Stramonium

Author(s) Mr. Ashish Dorage, Mr. Umesh Kamble, Mr. Rushikesh Takale, Miss. Mansi Katwate, Mr. Abhay Bobade, Miss. Harshada Jadhav, Mr. Sudheer Langare
Country India
Abstract In order to fight Candida albicans, a common fungal pathogen that causes a variety of illnesses, including oral and vaginal candidiasis, this study focusses on creating and testing an antifungal herbal gel with Datura stramonium extracts as the active ingredient. Alkaloids with antibacterial and antifungal qualities, including atropine, scopolamine, and hyoscyamine, are found in the plant Datura stramonium, which is well-known for its therapeutic uses. These bioactive substances will be extracted from the plant's leaves and added to a gel formulation as part of the experiment. By using techniques like Minimum Inhibitory Concentration (MIC) determination and antifungal activity assays, the gel's efficacy will be assessed based on its capacity to stop Candida albicans growth in vitro. Utilising Datura stramonium's inherent qualities for its possible medicinal use, the gel aims to offer a topical, simple-to-apply substitute for treating fungal infections. In order to guarantee the gel's safety and effectiveness as a topical antifungal treatment, the study also evaluates the gel's stability, pH, and risk for skin irritation. The project's overall goal is to provide a plant-based, sustainable treatment alternative with fewer adverse effects than traditional antifungal medications.
Keywords Formulation, Datura, Gel, Candida Albicans
Field Medical / Pharmacy
Published In Volume 16, Issue 2, April-June 2025
Published On 2025-04-09
Cite This Formulation & Evalution of Anti Fungal gel using Datura Stramonium - Mr. Ashish Dorage, Mr. Umesh Kamble, Mr. Rushikesh Takale, Miss. Mansi Katwate, Mr. Abhay Bobade, Miss. Harshada Jadhav, Mr. Sudheer Langare - IJSAT Volume 16, Issue 2, April-June 2025. DOI 10.71097/IJSAT.v16.i2.3475
DOI https://doi.org/10.71097/IJSAT.v16.i2.3475
Short DOI https://doi.org/g9fcf3

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