International Journal on Science and Technology

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Bacterial Genome Annotation Of Escherichia Coli

Author(s) Niranjana Sreenivasan, Moulya R Gowda, M D Yaana Muthamma, Shivandappa, Divyashree Kori, Navya N, Taru Das
Country India
Abstract Annotating the bacterial genome is essential for comprehending the genetic foundations of an organism's functions and behaviors. Escherichia coli serves as a well-researched model organism, and its genome annotation has been thoroughly examined. The E. coli genome includes four thousand two hundred and eighty eight protein-coding genes, of which thirty eight percent lack a defined function. Comparative genomics uncovers widespread and narrowly situated gene families, along with paralogous protein families, including the eighty ABC transporters. The genome is structured according to replication direction and includes insertion sequence elements, remnants of phages, and areas of atypical composition that suggest genome plasticity. Sophisticated bioinformatics tools and pipelines, including Galaxy, Prokka, Beav, and coliBASE, have been created to aid in E. coli genome annotation, offering insights into gene functionality, genome evolution, and species variation. These tools allow scientists to investigate the intricate biology of E. coli and its related species, promoting progress in areas like microbiology, genetics, and biotechnology.
Keywords Bacteria, genome, annotation, Escherichia coli, Galaxy
Field Biology > Genetics / Molecular
Published In Volume 16, Issue 1, January-March 2025
Published On 2025-02-11
Cite This Bacterial Genome Annotation Of Escherichia Coli - Niranjana Sreenivasan, Moulya R Gowda, M D Yaana Muthamma, Shivandappa, Divyashree Kori, Navya N, Taru Das - IJSAT Volume 16, Issue 1, January-March 2025. DOI 10.71097/IJSAT.v16.i1.1827
DOI https://doi.org/10.71097/IJSAT.v16.i1.1827
Short DOI https://doi.org/g85dmc
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